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ADR Term
ADReCS ID
MedDRA Code
MeSH ID
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Drug ID
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DrugBank ID
KEGG ID
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ADR Ontology
ADR Term
Inflammation
ADR ID
BADD_A05823
ADR Hierarchy
08
General disorders and administration site conditions
08.01
General system disorders NEC
08.01.05
Inflammations
08.01.05.007
Inflammation
Description
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. [MeSH]
MedDRA Code
10061218
MeSH ID
D007249
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Inflammation localised | Inflammation localized | Inflammation NOS | Inflammatory reaction | Inflammatory swelling | Inflammation | Exudative inflammation | Inflammations
ADR Related Proteins
Protein Name
UniProt AC
TTD Target ID
Interleukin-1 alpha
P01583
T16340
Interleukin-10
P29456
Not Available
Interleukin-6
P05231
T32578
Interleukin-8
P10145
T22658
Nuclear receptor subfamily 4 group A member 3
Q92570
T93949
Retinol-binding protein 1
P09455
Not Available
Tumor necrosis factor
P01375
T20178
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D01295
Linezolid
0.007547%
BADD_D01300
Lisinopril
-
-
BADD_D01311
Lomitapide
0.000121%
BADD_D01319
Lorcaserin hydrochloride
-
-
BADD_D01320
Lorcaserin hydrochloride hemihydrate
-
-
BADD_D01322
Losartan
0.000146%
BADD_D01324
Loteprednol etabonate
0.001097%
BADD_D01336
Macitentan
0.005773%
BADD_D01352
Maraviroc
-
-
BADD_D01359
Mechlorethamine
0.000799%
BADD_D01366
Medroxyprogesterone acetate
0.000766%
BADD_D01374
Meloxicam
0.000147%
BADD_D01393
Meropenem
-
-
BADD_D01401
Metformin
-
-
BADD_D01418
Methotrexate
0.008399%
BADD_D01420
Methoxsalen
-
-
BADD_D01431
Methylphenidate
-
-
BADD_D01433
Methylprednisolone
-
-
BADD_D01449
Metronidazole
0.000261%
BADD_D01455
Micafungin
-
-
BADD_D01470
Minocycline
0.000518%
BADD_D01477
Misoprostol
-
-
BADD_D01478
Mitomycin
0.000533%
BADD_D01496
Montelukast
-
-
BADD_D01498
Morphine
-
-
BADD_D01502
Moxifloxacin hydrochloride
-
-
BADD_D01507
Mycophenolate mofetil
0.002616%
BADD_D01508
Mycophenolic acid
0.001158%
BADD_D01515
Nafcillin
-
-
BADD_D01516
Nafcillin sodium
-
-
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