Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Inflammation
ADR ID BADD_A05823
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.05      Inflammations
08.01.05.007      Inflammation
Description A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. [MeSH]
MedDRA Code 10061218
MeSH ID D007249
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Inflammation localised | Inflammation localized | Inflammation NOS | Inflammatory reaction | Inflammatory swelling | Inflammation | Exudative inflammation | Inflammations
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Interleukin-1 alphaP01583T16340
Interleukin-10P29456Not Available
Interleukin-6P05231T32578
Interleukin-8P10145T22658
Nuclear receptor subfamily 4 group A member 3Q92570T93949
Retinol-binding protein 1P09455Not Available
Tumor necrosis factorP01375T20178
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01295Linezolid0.007547%
BADD_D01300Lisinopril--
BADD_D01311Lomitapide0.000121%
BADD_D01319Lorcaserin hydrochloride--
BADD_D01320Lorcaserin hydrochloride hemihydrate--
BADD_D01322Losartan0.000146%
BADD_D01324Loteprednol etabonate0.001097%
BADD_D01336Macitentan0.005773%
BADD_D01352Maraviroc--
BADD_D01359Mechlorethamine0.000799%
BADD_D01366Medroxyprogesterone acetate0.000766%
BADD_D01374Meloxicam0.000147%
BADD_D01393Meropenem--
BADD_D01401Metformin--
BADD_D01418Methotrexate0.008399%
BADD_D01420Methoxsalen--
BADD_D01431Methylphenidate--
BADD_D01433Methylprednisolone--
BADD_D01449Metronidazole0.000261%
BADD_D01455Micafungin--
BADD_D01470Minocycline0.000518%
BADD_D01477Misoprostol--
BADD_D01478Mitomycin0.000533%
BADD_D01496Montelukast--
BADD_D01498Morphine--
BADD_D01502Moxifloxacin hydrochloride--
BADD_D01507Mycophenolate mofetil0.002616%
BADD_D01508Mycophenolic acid0.001158%
BADD_D01515Nafcillin--
BADD_D01516Nafcillin sodium--
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